Both relax the small muscles behind expression lines, and both are botulinum toxin type A. But past that shared starting point, they behave differently enough that “which lasts longer?” isn’t a simple question.
What they are
Botox and Dysport are purified forms of botulinum toxin type A made by different manufacturers with their own formulation processes. Botox has been on the market longer, and many people use its name for any wrinkle relaxer.
How the formulations differ
The practical difference is protein size and dilution. Dysport’s molecules are generally considered smaller, which some providers believe lets it spread slightly more within the treated muscle. That’s why dosing isn’t a simple 1:1 conversion — an experienced injector adjusts units for each product.
How fast each works
Dysport tends to show visible softening a bit sooner — sometimes within two to three days — while Botox more commonly takes three to five. Both settle into full results around two weeks.
How long each lasts
For most patients, both last roughly three to four months. Areas with stronger movement, like the forehead or between the brows, may fade a little faster. Some people find Dysport wears off slightly sooner; others find the opposite — individual response matters more than brand.
| Feature | Botox | Dysport |
|---|---|---|
| Onset | 3–5 days | 2–3 days |
| Typical duration | 3–4 months | 3–4 months |
| Molecule size | Larger complex | Smaller complex |
| Best known for | Precision, fine lines | Faster onset, broader spread |
By area
For small, precise areas like crow’s feet, Botox is often favored for its more contained spread. For forehead lines, some providers prefer Dysport’s slightly wider diffusion to smooth a broader area with fewer injection points.
What affects longevity
- Dose — higher doses generally last longer, up to a point
- Muscle strength — very expressive muscles may metabolize product faster
- Consistency — regular treatment may help results last incrementally longer over time
The bottom line
They’re more alike than different, and longevity is close enough that onset speed, comfort, cost and your injector’s experience matter just as much. The best way to choose is a consultation with someone who has injected both extensively and can assess your facial movement in person. See our wrinkle relaxer options.


